Amenorrhea is the absence of menstruation in women who should have a regular menstrual cycle. This gynecological disorder can be a sign of various medical conditions and has significant implications for reproductive health.
There are two main types of amenorrhea:
- Primary amenorrhea: When a young woman has not had her first period (menarche) by age 15 or 16.
- Secondary amenorrhea: Occurs when a woman who has previously had regular periods stops menstruating for three months or more.
It is important to note that it is not always a sign of a serious illness, but it should be investigated to rule out health conditions.
Symptoms caused by amenorrhea
Amenorrhea is a symptom that can have multiple causes, ranging from temporary changes in the body to more serious medical conditions.
The main symptom of amenorrhea is the absence of menstruation, but depending on the underlying cause, other symptoms may appear, such as:
- Headaches.
- Blurred vision.
- Weight gain.
- Weight gain.
- Vaginal dryness.
- Pelvic pain.
- Changes in body hair growth.
Causes: Why does amenorrhea occur?
Amenorrhea can be caused by different factors. Among the most common causes we find:
Causes of primary amenorrhea
- Genetic or congenital abnormalities: Problems in the ovaries, uterus, or reproductive system that prevent menstruation.
- Hormonal problems: Disorders affecting the pituitary gland or hypothalamus, the glands responsible for regulating hormones.
- Low body weight or eating disorders: Anorexia or extreme low weight can disrupt hormone production.
Causes of secondary amenorrhea
- Pregnancy: It is the most common cause of amenorrhea in women of reproductive age.
- Breastfeeding: During the breastfeeding period, hormone levels can prevent menstruation.
- Stress: Extreme physical or emotional stress can affect the menstrual cycle.
- Polycystic ovary syndrome (PCOS):A hormonal disorder that affects the ovaries.
- Premature menopause:It occurs when the ovaries stop functioning before the age of 40.
- Thyroid disorders: Both hypothyroidism and hyperthyroidism can interfere with the menstrual cycle.
- Medications:Some contraceptives or medical treatments can interrupt menstruation.
Risk factors associated with amenorrhea
The risk factors associated with amenorrhea are diverse elements that can increase the likelihood of a woman developing this condition. These factors include both lifestyle-related aspects and underlying medical conditions. The main risk factors are outlined below:
Low body weight
Low body weight, especially when the body mass index (BMI) is below 18.5, can disrupt the menstrual cycle by altering the functioning of reproductive hormones. Eating disorders such as anorexia nervosa or bulimia are common causes of amenorrhea due to the extreme restriction of calories and nutrients needed for hormonal production.
Excessive physical exercise
Intense and prolonged exercise, particularly in sports that require low body weight or a high level of physical activity (such as gymnastics, ballet, or athletics), can affect estrogen levels and other hormonal regulators, resulting in amenorrhea.
Emotional or physical stress
Severe stress, whether emotional or physical, can trigger changes in the functioning of the hypothalamus, the region of the brain responsible for regulating the menstrual cycle. Chronic stress can disrupt hormonal balance, leading to the interruption of ovulation and menstruation.
Polycystic Ovary Syndrome (PCOS)
PCOS is a hormonal disorder that affects the ovaries, causing hormonal imbalances that can inhibit ovulation and cause amenorrhea. Women with PCOS often present elevated levels of androgens (male hormones) that interfere with the regular menstrual cycle.
Hormonal disorders
Problems with the glands that control reproductive hormones, such as the pituitary gland or the hypothalamus, can cause amenorrhea. Disorders such as hypothyroidism (low levels of thyroid hormones) or hyperprolactinemia (excessive production of prolactin) can disrupt the menstrual cycle.
Contraceptives and medications
The use of certain hormonal contraceptives, such as birth control pills, implants, or injectables, can cause amenorrhea. In some cases, menstruation does not return immediately after discontinuing these contraceptive methods. In addition, medications such as antipsychotics, antidepressants, or cancer treatments (chemotherapy) can also interfere with the menstrual cycle.
Family history
A family history of amenorrhea or other menstrual irregularities can increase the risk of developing this condition. Some women may have a genetic predisposition to hormonal disorders that affect menstruation.
Early menopause
Early menopause, or premature ovarian insufficiency, occurs when the ovaries stop functioning properly before the age of 40. Women with a family history of early menopause or certain autoimmune conditions have a higher risk of experiencing amenorrhea due to this cause.
Metabolic disorders
Metabolic diseases, such as uncontrolled diabetes or adrenal gland disorders, can dysregulate hormones and contribute to the onset of amenorrhea.
Medical procedures or surgeries
Surgeries on the uterus, ovaries, or pituitary gland can disrupt normal hormonal function and, as a result, cause amenorrhea. Additionally, medical procedures including radiation therapy or chemotherapy can affect ovarian function.
Substance use
Excessive consumption of alcohol or recreational drugs can alter hormone levels and negatively affect the menstrual cycle. Alcohol can influence the production of estrogen and progesterone, while drug use can have adverse effects on the glands that control reproduction.
Possible complications
Prolonged amenorrhea can have serious consequences for a woman's health, such as:
- Infertility: Lack of ovulation is one of the main causes of infertility in women with amenorrhea.
- Osteoporosis: Prolonged amenorrhea reduces estrogen levels, which can weaken bones and increase the risk of fractures.
- Cardiovascular problems: The hormonal imbalances associated with amenorrhea can increase the risk of heart disease.
Diagnosis and treatment of amenorrhea
One of the main problems associated with amenorrhea is infertility. In many cases, the absence of menstruation is linked to the lack of ovulation, making it difficult for women to conceive. However, with the appropriate treatment, many women with amenorrhea can restore their menstrual cycle and improve their chances of pregnancy.
The diagnosis of amenorrhea begins with a physical examination and a review of the patient's medical history. Depending on the symptoms, the doctor may recommend additional tests such as:
- Blood tests:To measure hormone levels.
- Pelvic ultrasound:To identify problems in the reproductive organs.
- MRI:It can be useful for detecting abnormalities in the pituitary gland.
On the other hand, treatment for amenorrhea depends on the underlying cause. Some options include:
- Lifestyle changes:If amenorrhea is caused by low body weight, stress, or excessive exercise, adjusting these factors can restore menstruation.
- Hormonal treatment:Hormonal contraceptives or hormone replacement therapy may be prescribed to regulate menstrual cycles.
- Treatment of underlying conditions:Conditions such as PCOS or thyroid disorders require specific treatments to restore hormonal balance.
- Surgery:If amenorrhea is caused by structural problems such as Asherman's syndrome, surgery may be necessary.
When should you consult a professional?
While not all causes of amenorrhea can be prevented, there are certain habits that can reduce the risk:
- Maintaining a healthy body weight.
- Avoiding extreme physical exercise.
- Managing stress effectively.
- Following appropriate medical monitoring if you have a history of hormonal or reproductive problems.
If you experience an absence of menstruation without apparent reason, it is important that you consult a doctor for a proper diagnosis. With the right treatment, most women can restore their menstrual cycle and improve their overall health.



